"When we spoke to director Paul W.S. Anderson prior to the start of Resident Evil: Afterlife (part four) he told us he had mapped out a story for a new trilogy which would carry the franchise into a sixth film, so you know he's ready. While we don't have a title for that sixth film, there is a confirmed release date...
ShockTillYouDrop.com has learned Sony/Screen Gems has set a debut date for September 12, 2014 which means Anderson and star Milla Jovovich will likely begin shooting the new film this fall."
Source: ShockTillYouDrop